Interleukin-18 Impairs the Pulmonary Host Response to Pseudomonas aeruginosa
نویسندگان
چکیده
منابع مشابه
Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa.
Interleukin-18 (IL-18) is a potent cytokine with many different proinflammatory activities. To study the role of IL-18 in the pathogenesis of Pseudomonas pneumonia, IL-18-deficient (IL-18(-/-)) and wild-type mice were intranasally inoculated with Pseudomonas aeruginosa. IL-18 deficiency was associated with reduced outgrowth of Pseudomonas in the lungs and diminished dissemination of the infecti...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2003
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.71.4.1630-1634.2003